Twenty-Five Years of Strain Imaging in Cardiac Function Assessment: Bibliometrics and Emerging Frontiers (2000–2025)

  • Xiaodi Chen The First College of Clinical Medical Science, China Three Gorges University, Yichang 443003, Hubei, China
  • Zhiyang Lv Department of Cardiology, Yichang Central People’s Hospital, Yichang 443003, Hubei, China
Keywords: Strain imaging, Global longitudinal strain, Speckle-tracking echocardiography, Cardiac function, Bibliometrics

Abstract

Objective: To perform a bibliometric analysis of global research trends in strain imaging for cardiac function assessment between 2000 and 2025. Methods: Publications were retrieved from the Web of Science Core Collection using terms related to “strain imaging” and “cardiac function.” Only English-language articles and reviews were included. A total of 2,890 publications were analyzed with VOSviewer to assess publication trends, key contributors, journals, keywords, and collaboration networks. Results: Annual publications increased exponentially, peaking in 2024, with nearly 2,400 cumulative papers by 2025. Chinese scholars, led by Mingxing Xie and Li Zhang, dominated in publication output, whereas international authors such as Thomas H. Marwick achieved higher citation impact. Huazhong University of Science and Technology ranked first in output, while the University of Oslo showed the highest average citation rate. Echocardiography was the most prolific journal, whereas Circulation: Cardiovascular Imaging and JACC achieved the greatest impact. Keyword analysis revealed a shift from methodological innovation to clinical applications and guideline-driven standardization. Collaboration networks highlighted the United States and China as global hubs, with Europe forming dense clusters. Conclusion: Strain imaging research has rapidly expanded and matured into an evidence-based clinical tool. Future efforts should focus on standardization, AI integration, disease-specific thresholds, and international collaboration.

References

Smiseth O, Torp H, Opdahl A, et al., 2016, Myocardial Strain Imaging: How Useful Is It in Clinical Decision Making. Eur Heart J, 37(15): 1196–1207.

Lyon A, López-Fernández T, Couch L, et al., 2022, 2022 ESC Guidelines on Cardio-Oncology Developed in Collaboration With the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS). Eur Heart J, 43(41): 4229–4361.

Kuwahara A, Iwasaki Y, Kobayashi M, et al., 2024, Artificial Intelligence-Derived Left Ventricular Strain in Echocardiography in Patients Treated With Chemotherapy. Int J Cardiovasc Imaging, 40(9): 1903–1910.

Thomas J, Edvardsen T, Abraham T, et al., 2025, Clinical Applications of Strain Echocardiography: A Clinical Consensus Statement From the American Society of Echocardiography Developed in Collaboration With the European Association of Cardiovascular Imaging of the European Society of Cardiology. Journal of the American Society of Echocardiography, S0894-7317(25): 00395-5.

Nyberg J, Jakobsen E, Østvik A, et al., 2023, Echocardiographic Reference Ranges of Global Longitudinal Strain for All Cardiac Chambers Using Guideline-Directed Dedicated Views. JACC Cardiovasc Imaging, 16(12): 1516–1531.

Sławiński G, Hawryszko M, Liżewska-Springer A, et al., 2023, Global Longitudinal Strain in Cardio-Oncology: A Review. Cancers (Basel), 15(3): 986.

Janwetchasil P, Yindeengam A, Krittayaphong R, 2024, Prognostic Value of Global Longitudinal Strain in Patients With Preserved Left Ventricular Systolic Function: A Cardiac Magnetic Resonance Real-World Study. J Cardiovasc Magn Reson, 26(2): 101057.

Published
2025-10-17