Dermatological Health https://www.bbwpublisher.com/index.php/DH <p style="text-align: justify;"><em>Dermatological Health</em> is a peer-reviewed, open access journal that publishes original research articles and review articles related to the prevention, diagnosis, and treatment of disorders of the skin, hair, and nails. The covered topics include, but are not limited to:&nbsp;clinical, investigative, and population-based studies, healthcare delivery and quality of care research,&nbsp;high quality, cost effective, and innovative treatments,&nbsp;new diagnostic techniques, and&nbsp;other topics related to the prevention, diagnosis, and treatment of disorders of the skin, hair, and nails.&nbsp;Each issue includes continuing medical education articles designed to fill practice and knowledge gaps in the delivery of dermatologic care.&nbsp;</p> Bio-Byword Scientific Publishing PTY LTD en-US Dermatological Health 3083-4775 Application Effect of Cosmetic Surgery Repair Techniques in the Treatment of Facial Trauma Patients https://www.bbwpublisher.com/index.php/DH/article/view/12362 <p><em>Objective</em>: To explore the application effect of cosmetic surgery repair techniques in the treatment of facial trauma. <em>Methods</em>: 200 patients with facial trauma who visited the hospital from January 2022 to December 2024 were selected and divided into an observation group and a control group according to the random number table method, with 100 cases in each group. The observation group was treated with cosmetic surgery repair techniques, while the control group was treated with traditional facial trauma repair techniques. The wound healing time, scar score, patient satisfaction, and complications were observed in both groups. <em>Results</em>: The average wound healing time in the observation group was 6.23 ± 1.05 days, which was significantly shorter than that in the control group (8.76 ± 1.32 days), and the difference was statistically significant (<em>P</em> &lt; 0.05). The average score of the Vancouver Scar Scale (VSS) in the observation group was 2.85 ± 0.76, which was significantly lower than that in the control group (5.12 ± 1.08), and the difference was statistically significant (<em>P</em> &lt; 0.05). The satisfaction rate of patients in the observation group was 90.00%, which was significantly higher than that in the control group (72.00%), and the difference was statistically significant (<em>P</em> &lt; 0.05). The incidence of complications in the observation group was 5.00%, which was significantly lower than that in the control group (16.00%), and the difference was statistically significant (<em>P</em> &lt; 0.05). <em>Conclusion</em>: Cosmetic surgery repair techniques have significant advantages in the treatment of facial trauma, which can effectively shorten the wound healing time, reduce scar formation, improve patient satisfaction, and reduce the incidence of complications. It is worthy of promotion and application in clinical practice.</p> Hangli Wu Qin Yin Wenjie Gao Copyright (c) 2025 Author(s) 2025-10-17 2025-10-17 3 3 1 7 10.26689/dh.v3i3.12362 Application of AI in the Design of Novel Peptide-based Ingredients for Skincare Products https://www.bbwpublisher.com/index.php/DH/article/view/12364 <p>This review provides a systematic review of the current applications and developmental trends of artificial intelligence (AI) in the design of novel peptide-based cosmetic ingredients. With rapid advancements in computational biology and artificial intelligence algorithms, the development paradigm for peptide-based skincare products is undergoing a revolutionary shift—from traditional trial-and-error screening to intelligent, precision-driven design. By leveraging machine learning algorithms, deep learning models, and molecular simulation techniques, artificial intelligence has significantly enhanced the efficiency and success rate of peptide ingredient development while reducing associated costs. The review highlights breakthroughs in artificial intelligence applications for peptide molecular design, stability optimization, transdermal delivery prediction, and efficacy evaluation. It also explores the integration of artificial intelligence with interdisciplinary fields such as synthetic biology and nanotechnology, and offers insights into current challenges and future development directions.</p> Youmin Zhu Junfeng Zhao Yuncai Tian Copyright (c) 2025 Author(s) 2025-10-17 2025-10-17 3 3 8 11 10.26689/dh.v3i3.12364 Development, Classification, Application, and Research Progress of Modern Skin Photoaging Assessment Tools https://www.bbwpublisher.com/index.php/DH/article/view/12365 <p>Skin photoaging, a degenerative process caused by ultraviolet radiation, plays a pivotal role in clinical diagnosis and anti-aging research. This paper systematically reviews the evolution of skin photoaging assessment tools, tracing their development from traditional clinical scoring systems to modern imaging technologies, biomarker detection, and AI-assisted analysis. It provides detailed categorization, application scenarios, and comparative evaluations of these methodologies. The study reveals that single-assessment tools have inherent limitations, while multimodal integrated evaluation has emerged as the prevailing approach. Future efforts should focus on integrating molecular biology and AI technologies to establish a more precise photoaging assessment framework.</p> Ruini Yang Zhi Yang Copyright (c) 2025 Author(s) 2025-10-17 2025-10-17 3 3 12 20 10.26689/dh.v3i3.12365 Observation on the Clinical Efficacy of Microneedle Radiofrequency Combined with Bear Bile Powder in the Treatment of 40 Cases of Moderate to Severe Acne https://www.bbwpublisher.com/index.php/DH/article/view/12361 <p><em>Objective</em>: To observe the clinical efficacy of microneedle radiofrequency combined with bear bile powder in the treatment of 40 cases of moderate to severe acne. <em>Methods</em>: 80 patients with moderate to severe acne admitted from July 2020 to July 2023 were selected as the study subjects. They were divided into two groups using a random number table method. The control group (40 patients) received microneedle radiofrequency treatment alone, while the observation group (40 patients) received a combination of microneedle radiofrequency and bear bile powder treatment. The treatment effects, skin lesion conditions [Global Acne Grading System (GAGS)], and adverse reactions were compared between the two groups. <em>Results</em>: The total effective rate of the observation group was 100.00%, which was higher than 87.50% of the control group (<em>P</em> &lt; 0.05). After 4, 8, and 12 weeks of treatment, the GAGS scores of the observation group were lower than those of the control group (<em>P</em> &lt; 0.05). There was no difference in the incidence of adverse reactions between the two groups (<em>P</em> &gt; 0.05). <em>Conclusion</em>: Microneedle radiofrequency combined with bear bile powder can effectively treat moderate to severe acne, improve skin lesion conditions, and ensure treatment safety.</p> Yansheng Zeng Weihua Zeng Zhuli Chen Suhong Liu Xuesheng Zhang Copyright (c) 2025 Author(s) 2025-10-17 2025-10-17 3 3 21 27 10.26689/dh.v3i3.12361 Analysis of Clinical Effectiveness of Intense Pulsed Light Combined with Q-Switched Laser in Facial Skin Beauty Treatment https://www.bbwpublisher.com/index.php/DH/article/view/12363 <p><em>Objective</em>: To investigate and analyze the clinical effectiveness of intense pulsed light combined with Q-switched laser in facial skin beauty treatment. <em>Methods</em>: A total of 197 patients with post-acne pigmented spots and erythema seeking facial skin beauty treatment in our hospital from May 2024 to May 2025 were selected and randomly divided into observation group (99 cases) and control group (98 cases) according to the envelope method. The control group was treated with a Q-switched laser, while the observation group was treated with intense pulsed light combined with a Q-switched laser. The clinical effectiveness, Melasma Area and Severity Index (MASI) score, and skin barrier function (stratum corneum water content, transepidermal water loss, epidermal sebum content) were compared between the two groups. <em>Results</em>: The clinical effectiveness of the observation group was significantly better than that of the control group (<em>P</em> &lt; 0.05). There was a statistically significant difference in the decrease of MASI scores between the observation group and the control group (<em>P</em> &lt; 0.05). After treatment, the levels of transepidermal water loss and epidermal sebum content in both groups were significantly reduced, and the water content of the stratum corneum was significantly increased. The improvement of each index in the observation group was better than that in the control group (<em>P</em> &lt; 0.05). <em>Conclusion</em>: The combination of intense pulsed light and Q-switched laser can not only improve the clearance rate of skin lesions, but also achieve an overall improvement in skin barrier function by promoting collagen regeneration, optimizing epidermal hydration function, and sebum metabolism.</p> Xuefen Wang Yaqi Yu Yan Ma Ruonan Wang Bingbing Gao Xuemei Ma Copyright (c) 2025 Author(s) 2025-10-17 2025-10-17 3 3 28 34 10.26689/dh.v3i3.12363