Evaluation of the Effectiveness, Accuracy, Specificity, and Sensitivity of High-Frequency Ultrasound in Differentiating Benign and Malignant Breast Micronodules
Abstract
Objective: To analyze the significance of high-frequency ultrasound in differentiating benign and malignant breast micronodules. Methods: Eighty-five patients with breast micronodules admitted for diagnosis between October 2022 and October 2024 were selected for high-frequency ultrasound diagnosis. The diagnostic efficacy of high-frequency ultrasound was evaluated by comparing it with the results of surgical pathology. Results: High-frequency ultrasound detected 50 benign nodules, primarily breast fibroadenomas, and 35 malignant nodules, mainly breast ductal carcinoma in situ. Based on surgical pathology results, the diagnostic accuracy of high-frequency ultrasound was 96.47%, specificity was 97.96%, and sensitivity was 94.44%. In high-frequency ultrasound diagnosis, the proportion of grade III and IV blood flow in malignant nodules was higher than that in benign nodules, while the proportion of regular shape and clear margins was lower. The proportion of microcalcifications and posterior echo attenuation was higher in malignant nodules, and the resistance index (RI) and peak blood flow velocity were lower than those in benign nodules (P < 0.05). Conclusion: High-frequency ultrasound can effectively differentiate benign and malignant breast micronodules, determine specific nodule types, and exhibits high diagnostic accuracy and sensitivity. Additionally, benign and malignant nodules can be differentiated based on the grading of blood flow signals, sonographic features, and blood flow velocity, providing reasonable guidance for subsequent treatment plans.
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