In recent years, the demand for orthopedic implants in the medical field has been continuously increasing. At present, clinical personnel need to pay attention to various performance aspects of orthopedic implants when applying them, such as strength, wear resistance, corrosiveness, antibacterial properties, etc. In terms of surface modification of orthopedic implants, clinical personnel can apply plasma spraying technology. This technology can not only improve surface hardness and wear resistance, enhance biocompatibility and osteogenic ability, but also achieve antibacterial treatment, which helps to improve the clinical treatment effect of orthopedics. To this end, the article explores plasma spraying technology and orthopedic implants, analyzes the application of plasma spraying technology in surface modification of orthopedic implants, and raises some application issues from an industry perspective, hoping to improve the application effect of plasma spraying technology, promote research in the field of surface modification of orthopedic implants, and help better develop clinical treatment in orthopedics in China.