Exploration of the Value of Extract of Wuwei Xiaodu Drink on Rabbit Model of Spinal Infection

© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )

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Abstract

Objective: To study the therapeutic effect of the Extract of Wuwei Xiaodu Drink on spinal infection and provide the scientific basis for clinical application. Methods: By establishing a rabbit model of spinal infection, this paper observed and analyzed the changes in body mass before and after the intervention and the comparison of inflammation-related factors and blood leukocyte counts among the three groups. Results: There was a significant difference in the changes in body mass of rabbits before and after intervention in the experimental group, control group and blank group (P < 0.05); there was no statistically significant difference in calcitoninogen, C-reactive protein and routine blood leukocyte counts between the experimental group and the control group (P > 0.05), and there was a statistically significant difference in calcitoninogen, C-reactive protein and routine blood leukocyte counts between the experimental group and the blank group (P < 0.05). Conclusion: The Extract of Wuwei Xiaodu Drink can play a protective role by regulating the level of inflammatory factors in blood routine leukocyte count and reducing the inflammatory reaction in the spinal cord injury area.

References

Li Y, Yan P, Liu J, et al., 2022, Study on the In Vitro Inhibitory Effect of Different Polar Parts of Wuwei Xiaodu Drink on Porcine Microvirus. Animal Husbandry and Veterinary Medicine, 54(9): 114–121.

Zhang X, Fang Q, Shu Q, et al., 2023, Effect of Wuwei Xiaodu Drink Flushing and Suctioning Oral Care on Aspiration Pneumonia and Prognosis of Stroke Patients. Modern Practical Medicine, 35(1): 109–111.

Feng H, Wang Y, Yang Y, et al., 2023, Effects of Yin Qiao San Combined with Wuwei Xiaodu Drink Plus and Minus on the Improvement of Symptoms and Blood WBC, PCT, and CRP Levels in Pediatric Acute Suppurative Tonsillitis. World Journal of Integrative Medicine, 18(5): 1018–1022, 1040.

Peng Q, Huang M, Sun M, 2023, Clinical Observation on Acute Pelvic Inflammatory Disease Treated with Wuwei Xiaodu Drink Combined with Acupuncture and Charging Ren and Renji Chakra Points. West Chinese Medicine, 36(4): 93–96.

Liu S, Peng J, Tang L, et al., 2024, Effect of Bazhen Tang Combined with Wuwei Xiaodu Drink Plus and Minus on the Therapeutic Efficacy and Quality of Survival of Patients with Locally Advanced Nasopharyngeal Carcinoma of Qi and Yin Deficiency Type Treated with Concurrent Radiotherapy. Chinese Journal of Clinical Physicians, 52(1): 115–118.

Xie Y, Chen Y, Mao M, 2023, Observation on the Efficacy of Wuwei Xiaodu Drink Medicated Thread Drainage in the Treatment of Pediatric Perianal Abscess. Journal of Practical Chinese Medicine, 39(2): 262–263.

Cheng Z, Zhang B, Tang L, 2024, Effect of Wuwei Xiaodu Drink Therapy on Stoma Complications in Patients with Urinary Stoma for Bladder Cancer. Practical Clinical Medicine, 25(1): 87–90, 105.

Zhang Q, Wang H, Wu C, et al., 2023, Observations on the Therapeutic Effect of Wuwei Xiaodu Drink Plus Huang Mudan Tang in the Adjuvant Treatment of Acute Pelvic Inflammatory Disease of Heat-Toxin Stasis Type. Journal of Practical Chinese Medicine, 39(11): 2221–2223.

Zhu H, Chen F, Nie C, et al., 2023, Clinical Study on Radiation Oesophagitis Treated with Sha Shen Maitong Tang Combined with Wuwei Xiaodu Drink. Journal of Practical Chinese Medicine, 39(9): 1739–1741.

Luo Y, Guan X, Lu X, et al., 2022, Clinical Observation of Wuwei Xiaodu Drink Combined with Antibiotics in the Treatment of Catheter-Associated Urinary Tract Infection. Chinese Medicine and Clinic, 13(1): 51–54, 65.

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