ARTICLE
Volume 4,Issue 3
28 May 2025
Clinical Study of 60 Cases of Deep Cervical Lymphatic-Venous Anastomosis for the Treatment of Alzheimer’s Disease
Jia Liu ,
Fanpeng Meng ,
Yanli Guo ,
Qinghuai Xu
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1
Armed Police Shandong General Hospital, Jinan 250000, Shandong Province, China,
2
Yinfeng (Jinan) Hospital, Jinan 250000, Shandong Province, China,
3
Yinfeng (Jinan) Hospital, Jinan 250000, Shandong Province, China; Department of Neurosurgery, Affiliated Hospital of Beijing University of Chinese Medicine, Beijing 102401, China,
CNR 2025 , 3(2), 62–69;
https://doi.org/10.26689/cnr.v3i2.11146
© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract
Objective: To analyze the therapeutic effect of deep cervical lymphatic-venous anastomosis (LVA) on Alzheimer’s disease (AD). Methods: 120 patients with AD who were admitted to the hospital between December 2022 to December 2024 were selected and randomly divided into two groups using a random number table. The experimental group received LVA treatment, while the control group received transcranial magnetic stimulation combined with medication. The total effective rate, cognitive function score, language expression, cerebrospinal fluid biomarkers, and adverse reaction rate were compared between the two groups. Results: The total effective rate of the experimental group was higher than that of the control group. The cognitive function score and cerebrospinal fluid biomarkers of the experimental group after treatment were better than those of the control group (P < 0.05). The adverse reaction rate in the experimental group was similar to that in the control group (P > 0.05). Conclusion: LVA can improve the clinical efficacy of patients with AD, enhance their cognitive function and language expression, regulate the level of cerebrospinal fluid biomarkers, and has high surgical safety.
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