Objective: To study the effect of cardiac rehabilitation nursing after coronary heart disease interventional therapy. Methods: 80 patients with coronary heart disease who underwent interventional treatment from January 2024 to August 2024 were selected as experimental subjects and randomly divided into 40 cases in each group. The patients in the Kanghu group received cardiac rehabilitation care after interventional treatment, and the patients in the relative group received clinical routine care after interventional treatment. Cardiac function indicators, 6-minute walking distance, quality of life, incidence of adverse cardiovascular events, and nursing satisfaction were compared and analyzed. Results: Before nursing, there was little difference in cardiac function indicators between groups and no statistical significance (P > 0.05); after nursing, the cardiac function indicators between groups were optimized, and the cardiac function indicators in the Kanghu group were better than those in the relative group, which was statistically significant (P < 0.05). Before surgery, the 6-minute walking distance between the groups was similar, which was not statistically significant (P > 0.05); after surgery, the 6-minute walking distance between the groups increased, and the 6-minute walking distance in the Kangwu group was longer than that in the relative group, which was statistically significant (P < 0.05). There was a large difference in the quality of life scores between the groups, and the quality of life score in the Kangwu group was higher than that in the relative group, which was statistically significant (P < 0.05). The incidence of adverse events in the Kangwu group was lower than that in the relative group, and the difference was statistically significant (P < 0.05). Conclusion: The effect of receiving cardiac rehabilitation care after interventional treatment for coronary heart disease is ideal, which is helpful to strengthen the cardiac function of patients and speed up the recovery speed.