ARTICLE
Volume 4,Issue 2
2 July 2025
Key Points of“Treatment Algorithm for Pulmonary Arterial Hypertension” from the 7th World Symposium on Pulmonary Hypertension and Its Impact on PAH Treatment in China
Songlin Zhang ,
Ashfaq Ahmad ,
Qian Ren ,
Heng Wang ,
Lingling Li ,
Xiaoyu Wang ,
Yajuan Du ,
Fenling Fan
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1
The First Affiliated Hospital of Xi’an Jiaotong University,
2
Sunsimiao Hospital, Beijing University of Chinese Medicine,
CR 2025 , 3(2), 22–27;
https://doi.org/10.26689/cr.v3i2.10859
© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract
Following the 7th World Symposium on Pulmonary Hypertension in 2024, the European Respiratory Journal published an updated treatment algorithm for pulmonary arterial hypertension (PAH), highlighting the emerging role of the activin signal inhibitor (ASI) sotatercept, as a key therapeutic advancement. The updated plan underscores the importance of indicators such as World Health Organization (WHO) functional class and 6-minute walk distance (6MWD) in risk assessment. It advocates for a personalized treatment approach based on risk stratification, encompassing both initial therapy selection and escalation strategies during follow-up. The anticipated introduction of the novel ASI sotatercept in China is expected to expand the therapeutic landscape for PAH management in the country.
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