Clinical Diagnostic Value of Serum Low-Density Lipoprotein Cholesterol Combined with Carotid Artery Ultrasound Parameters in Patients with Coronary Heart Disease

Hongping Lu, Qilong Chen

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¹ Helie Street Community Health Service Center, Wuxi 214100, Jiangsu, China,

² Department of Medical Imaging, Wuxi No. 9 People’s Hospital, Wuxi 214100, Jiangsu, China,

CR 2025 , 3(4), 60–66; https://doi.org/10.26689/cr.v3i4.13499

© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )

Abstract

Objective: To analyze and study the results of carotid artery ultrasound examination and serum low-density lipoprotein cholesterol (LDL-C) detection in patients with coronary heart disease, aiming to explore their application effectiveness and value in the clinical diagnosis of coronary heart disease. Methods: A retrospective analysis was conducted on the diagnostic conditions of suspected coronary heart disease patients who visited our hospital from May 2023 to June 2025. Using coronary angiography results as the gold standard, 60 patients diagnosed with coronary heart disease were selected as the study group, and 60 patients without coronary heart disease were selected as the control group. LDL-C levels and carotid artery ultrasound parameters were compared between the two groups to evaluate their diagnostic value. Results: The IMT and plaque semi-quantitative scores in the study group were higher than those in the control group (P < 0.05); carotid artery plaques were detected in 47 patients in the study group, with a total of 103 plaques. The proportion of patients with ≥ 2 types of plaques was 66.67%, mainly consisting of heterogeneous plaques (34.95%) and soft plaques (56.31%), which were significantly higher than those in the control group (P < 0.05); LDL-C and TC levels in the study group were significantly higher than those in the control group (P < 0.05). Conclusion: The detection of serum LDL-C and carotid artery ultrasound parameters holds significant application value in the diagnosis of coronary heart disease (CHD). A combined detection approach can serve as an important reference for screening coronary artery lesions and provide a reference basis for formulating clinical diagnosis and treatment strategies.

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