Observation on the Clinical Efficacy of Microneedle Radiofrequency Combined with Bear Bile Powder in the Treatment of 40 Cases of Moderate to Severe Acne

Yansheng Zeng, Weihua Zeng, Zhuli Chen, Suhong Liu, Xuesheng Zhang

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¹ Ganzhou Dermatosis Hospital, Ganzhou 341000, Jiangxi, China,

DH 2025 , 3(3), 21–27; https://doi.org/10.26689/dh.v3i3.12361

© 2025 by the Authors. Licensee: Bio-Byword Scientific Publishing Pty Ltd, Australia. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )

Abstract

Objective: To observe the clinical efficacy of microneedle radiofrequency combined with bear bile powder in the treatment of 40 cases of moderate to severe acne. Methods: 80 patients with moderate to severe acne admitted from July 2020 to July 2023 were selected as the study subjects. They were divided into two groups using a random number table method. The control group (40 patients) received microneedle radiofrequency treatment alone, while the observation group (40 patients) received a combination of microneedle radiofrequency and bear bile powder treatment. The treatment effects, skin lesion conditions [Global Acne Grading System (GAGS)], and adverse reactions were compared between the two groups. Results: The total effective rate of the observation group was 100.00%, which was higher than 87.50% of the control group (P < 0.05). After 4, 8, and 12 weeks of treatment, the GAGS scores of the observation group were lower than those of the control group (P < 0.05). There was no difference in the incidence of adverse reactions between the two groups (P > 0.05). Conclusion: Microneedle radiofrequency combined with bear bile powder can effectively treat moderate to severe acne, improve skin lesion conditions, and ensure treatment safety.

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