This study investigates the intervention effects of a multidimensional wellness model on cognitive function and quality of life in elderly patients with mild cognitive impairment (MCI). Through a randomized controlled trial, 60 elderly MCI patients from Yikang Nursing Home in Shanghai were evenly divided into an intervention group and a control group, receiving either the multidimensional wellness model or routine management for a 3-month intervention period. Results demonstrated significant improvements in both cognitive function and quality of life in the intervention group. The MMSE total score increased by 16.2%, with orientation ability, memory, attention/calculation, recall capacity, and language improving by 22.7%, 18.8%, 20.4%, 36.8%, and 3.0%, respectively. Activities of daily living (ADL) scores rose by 37.5%, the completion rate of instrumental activities of daily living increased from 28% to 65%, and the incidence of falls decreased by 54%. The study indicates that the multidimensional wellness model effectively enhances cognitive function and quality of life in elderly MCI patients, demonstrating significant clinical value for widespread application.