Against the backdrop of the construction industry’s transition towards industrialization and intelligence, prefabricated buildings have emerged as a core direction for promoting high-quality development in the sector. BIM (Building Information Modeling) technology, as a pivotal tool for lifecycle management in prefabricated buildings, directly influences the effectiveness of professional talent cultivation. The blended teaching model, which integrates the advantages of online and offline instruction, breaks through the temporal and spatial constraints of traditional teaching. Meanwhile, the rapid development of AIGC (Artificial Intelligence Generated Content) technology offers new solutions to address challenges in BIM teaching for prefabricated buildings, such as insufficient practical scenarios, lack of personalized guidance, and outdated teaching resources. This paper analyzes the current status and pain points of BIM teaching for prefabricated buildings under the blended teaching model and proposes targeted application strategies and safeguard measures. The aim is to optimize the BIM teaching process, enhance teaching efficiency and quality, cultivate compound talents in BIM for prefabricated buildings who meet industry demands, and provide theoretical references and practical insights for the reform of teaching in the prefabricated building field.