When the plant-mixed thermal regeneration technology is adopted for the waste asphalt pavement mixtures, its performance can basically reach the level of freshly-mixed asphalt concrete, which can be used for paving the middle and lower layers of road pavements of various grades. Through the research and application of plant-mixed thermal regeneration technology based on China's Kunming-Yuxi Expressway Pavement Overhaul Project, this paper summarizes relevant technical points and effectively advocates the promotion and application of this technology in highway maintenance.