In recent years, relevant government departments have achieved the goal of reduction and harmless application through the development and implementation of municipal waste incineration power plants, in order to advocate ecological and environmental protection. At present, in order to further achieve the goal of sustainable development, municipal waste incineration power plants have actively responded to the national call and requirements as well as made overall arrangements for the energy-saving design and optimization design of their internal system. Therefore, with the concept of sustainable development, this paper studies and analyzes the problems of the HVAC design as well as suggests related strategies for municipal waste incineration power plants in order to provide relevant reference.