As a crucial pivot for national strategic development, the university relocation project in Xiong’an New Area undertakes the mission of optimizing capital functions and promoting regional coordinated development. Taking the Xiong’an Campus of China University of Geosciences (Beijing) as a case study, this paper explores the collaborative pathways between universities and cities in terms of functional complementarity, resource sharing, and ecological symbiosis from the perspective of campus functional layout and spatial optimization. By integrating four core concepts—green ecology, intelligent technology, cultural inheritance, and traffic optimization—it proposes a design strategy of “breaking boundaries and multi-dimensional linkage,” aiming to construct a new spatial paradigm of urban-university integration and provide theoretical support and practical references for the development of higher education and urbanization in Xiong’an New Area.