Higher education is undergoing digital construction, and traditional education can no longer meet the training needs of nursing talents in the new era. The teaching of Fundamentals of Nursing faces several dilemmas, including cumbersome course content and scattered knowledge points. With the iterative update of modern digital technologies, the knowledge graph—structured, semantic, scalable, and multi-source integrated—provides a technical path to solve these problems. This study proposes a planned teaching application scheme based on the Xuexitong platform, which integrates the knowledge graph, artificial intelligence teaching assistant, and task engine. This scheme not only provides practical reference for the teaching innovation of Fundamentals of Nursing but also offers new ideas for the in-depth integration of educational technology and nursing teaching.