The construction of emerging engineering disciplines focuses on industrial transformation and upgrading as well as talent demands in emerging chemical sectors, putting forward innovation requirements for the traditional classroom teaching of Chemical Engineering Principles. As a core course linking basic theories and engineering applications for chemical majors, it is confronted with prevalent practical difficulties including abstract theoretical formulas, disconnection between classroom lectures and industrial realities, and separation of theoretical learning from practical application. Based on the talent cultivation objectives of emerging engineering education, this paper takes integrating theoretical knowledge into the classroom and connecting classroom teaching with engineering scenes as the core idea, and constructs a new integrated teaching mode from four dimensions: reconstruction of teaching content, innovation of classroom teaching methods, integrated design of theory and practice, and diversified assessment mechanisms. Classroom practice is carried out around typical unit operations such as fluid transportation, heat transfer, and distillation. Practical results show that the integrated classroom can reduce students’ difficulty in understanding theories and strengthen their engineering thinking, meeting the employment standards of emerging engineering industries including the new energy chemical industry and the green chemical industry. It can provide references for classroom reform of similar engineering majors.