This article focuses on the study of high school English teaching strategies from an interdisciplinary perspective. Through an in-depth analysis of the significance and implementation path of interdisciplinary teaching in high school English education, combined with practical teaching cases to explore how to effectively integrate knowledge from other disciplines with English teaching, this study aims to provide a useful reference for improving the quality of high school English teaching and cultivating students’ comprehensive literacy. Interdisciplinary teaching can significantly stimulate students’ interest in learning and improve their language proficiency and interdisciplinary thinking, laying a solid foundation for their future development.