The advent of the “Internet Plus” era has brought unprecedented challenges to the cultivation of computer science talents. To cultivate computer science professionals who meet the demands of this new era, it is imperative to conduct in-depth reforms in the course content and teaching mode of computer science. Therefore, this paper systematically explores the reform path of course content and teaching mode for computer science under the background of “Internet Plus,” aiming to provide a concrete and operable reference plan for the teaching reform of computer science and effectively enhance the quality of talent cultivation and its alignment with industry needs.