Clinical Application of Guizhi Longgu Muli Decoction Combined with Traditional Chinese Medicine Foot Bath and Five-Tone Therapy in the Treatment of Insomnia

Zhigang Xu

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¹ Jurong Hospital of Traditional Chinese Medicine, Zhenjiang 212400, Jiangsu, China,

JCNR 2026 , 10(3), 281–288; https://doi.org/10.26689/jcnr.v10i3.14632

© 2026 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )

Abstract

Objective: To evaluate the therapeutic effect of Guizhi Longgu Muli Decoction combined with traditional Chinese medicine (TCM) foot bath and five-tone therapy on insomnia. Methods: A total of 99 patients with insomnia admitted to the hospital from October 2023 to October 2025 were selected and equally divided using a random number table. Group A received Guizhi Longgu Muli Decoction treatment, Group B received Guizhi Longgu Muli Decoction combined with TCM foot bath treatment, and Group C received Guizhi Longgu Muli Decoction combined with TCM foot bath and five-tone therapy. The therapeutic effects among the groups were compared. Results: The total effective rate in Group C was higher than that in Groups A and B. The sleep quality score and TCM syndrome score after treatment in Group C were lower than those in Groups A and B, and the scores in Group B were lower than those in Group A (p < 0.05). There was no significant difference in the adverse reaction rates among the three groups (p > 0.05). Conclusion: Administering Guizhi Longgu Muli Decoction combined with TCM foot bath and five-tone therapy to patients with insomnia can improve insomnia symptoms, enhance sleep quality, and demonstrate high treatment safety and definite efficacy.

References

Cai Y, Zhang X, Li J, et al., 2025, Evaluation of Effect of Modified Guizhi Gancao Longgu Muli Decoction in Treating Menopausal Insomnia. Liaoning J Tradit Chin Med, 52(5): 92–96.

Zhu X, Zeng H, Zhu S, et al., 2025, Clinical Observation on Therapeutic Effect of Fuzi Decoction Combined with Guizhi Gancao Longgu Muli Decoction in Treating Insomnia Due to Heart–Kidney Yang Deficiency. Chin Arch Tradit Chin Med, 43(11): 200–203.

Yang X, Liu Z, Song J, 2025, Effect of Auricular Point Sticking Combined with Guizhi Longgu Muli Decoction on Preoperative Insomnia in Patients with Uterine Fibroids. Mod Diagn Treat, 36(16): 2406–2408.

Wang H, Sun Y, Wang X, et al., 2024, Effect of Guizhi Longgu Muli Decoction Combined with Acupuncture in Treating Malignancy-Related Insomnia. Chin Arch Tradit Chin Med, 42(7): 210–213.

Han L, Xu M, Mo Z, 2024, Clinical Efficacy of Acupuncture Combined with Guizhi Longgu Muli Decoction in Treating Chronic Insomnia. Shenzhen J Integr Tradit Chin West Med, 34(6): 56–59.

Mao X, Xu S, 2026, Effect of Modified Suanzaoren Decoction Combined with TCM Foot Bath on Sleep Quality in Patients with Refractory Insomnia Undergoing Maintenance Hemodialysis. Chin J Mod Drug Appl, 20(6): 117–120.

Chen Z, Yang H, Lu Y, 2025, Clinical Observation on Acupuncture Combined with TCM Foot Bath in Treating Insomnia After Ischemic Stroke. J Pract Tradit Chin Med, 41(9): 1778–1780.

Liu H, Ding X, Guo L, 2025, Effect of Miao Medicine Foot Bath Combined with TCM Medicinal Pillows on Sleep and Blood Pressure in Hemodialysis Patients with Insomnia. J Chin Ethnic Med, 31(7): 14–16.

Xie Q, Wu S, Cai Y, 2025, Clinical Study on Efficacy of Gua Sha Combined with Psychological Music Intervention in Treating Insomnia. World J Sleep Med, 12(2): 430–433.

Liu X, Meng X, Wang L, et al., 2025, Effects of Five-Element Music and Language Induction Combined with Zhan Zhuang on Sleep and Psychology in Hypertension Patients with Liver Yang Hyperactivity Insomnia. Beijing J Tradit Chin Med, 44(8): 1002–1006.

Yao L, Zhu X, He Y, et al., 2025, Application of Gua Sha Combined with Five-Element Music Based on Meridian Theory in Treating Stomach Meridian Pain with Insomnia Due to Liver–Stomach Qi Stagnation. J Pract Intern Med Tradit Chin Med, 39(1): 133–136.

Qu Y, Bai X, 2025, Effect of Nursing Intervention Based on Timeliness Incentives Combined with Five Elements Music Therapy Timed by Midnight–Noon Ebb–Flow Theory on Sleep Quality in Post-Stroke Insomnia. Clin Res Pract, 10(4): 159–162.

Sun X, 2024, Effect of Auricular Point Pressing with Beans Combined with Five Elements Music Intervention on TCM Symptom Scores and Sleep Quality in Post-Cerebral Infarction Insomnia. Reflex Ther Rehabil Med, 5(2): 42–45.

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