Background: With the accelerating global population aging, health issues related to menopausal syndrome in women are becoming increasingly prominent. Although related research and guidelines continue to enrich, problems such as fragmented knowledge and dispersed research efforts constrain the improvement of nursing quality.​Objective: To analyze and summarize current research trends and hot topics in women’s health concerning menopausal syndrome, and to explore the forefront development directions in this field.​Methods: Based on literature retrieved from the China National Knowledge Infrastructure (CNKI) and Web of Science (WOS) databases from their inception to December 2024, this study ultimately included 639 articles (256 in Chinese, 383 in English). Using CiteSpace software, a bibliometric and visual analysis was conducted to construct knowledge maps of countries, institutions, authors, and keywords. Results: The overall publication volume of both Chinese and English literature showed an upward trend. English publications reached 53 in 2024, while Chinese publications peaked at 30 in 2019. The United States led in publication output (117 articles, 21.91%). Among Chinese institutions, the highest publication count was only 2 articles. Keyword analysis revealed that “menopausal syndrome” and “psychological care” were hot topics in Chinese literature (frequencies 51, 40), whereas “symptoms” and “quality of life” were high-frequency keywords in English literature (frequencies 98, 78). The cluster structures were significant (Q > 0.53, S > 0.78), and burst term analysis indicated an evolution in research focus from symptomatic care towards personalized interventions. Conclusions: Knowledge graph visualization can clearly present the development context and hotspot differences in research on nursing care for women with menopausal syndrome, providing a reference for subsequent studies.