ARTICLE

Volume 10,Issue 7

All Issues
Submit to JCNR
Cite this article
1
Citations
1
Views
30 June 2026
Study on the Correlation Between Preoperative Anemia and Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy
Xu Hu ,  Shengping Zheng ,  Lun Mao ,  Chaolong Liu ,  Mingquan Wang
Show Less
1 Department of Anesthesiology, Zizhong County People’s Hospital, Neijiang 641200, Sichuan, China,
JCNR 2026 , 10(6), 258–264; https://doi.org/10.26689/jcnr.v10i6.15567
© 2026 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Download PDF
Cite
XML
HTML
Abstract

Objective: To investigate the correlation between preoperative anemia and postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy (LC), and to analyze 14 influencing factors of PONV to provide references for clinical prevention and treatment. Methods: A prospective cohort study was conducted, including 400 patients who underwent LC in our hospital from June 2024 to May 2026. Patients were grouped based on the occurrence of postoperative PONV, and the incidence of PONV was compared between anemic and non-anemic patients. Univariate and multivariate logistic regression analyses were used to analyze the influencing factors of PONV. Results: In the PONV group, the proportion of anemic patients was higher than that of non-anemic patients, but the difference was not statistically significant (p = 0.069). There were statistically significant differences in baseline data, such as gender, history of motion sickness, and postoperative opioid analgesia, between the two groups (all p < 0.05). Univariate regression analysis of five potential factors showed that three factors, namely female gender, history of motion sickness, and postoperative opioid analgesia, were significantly associated with PONV (all p < 0.05). Multivariate regression analysis revealed that female gender, history of motion sickness, and postoperative opioid analgesia were independent risk factors for PONV after LC (p < 0.05). Conclusion: Female gender, history of motion sickness, and postoperative opioid analgesia are closely related to PONV and are independent risk factors for PONV in patients undergoing LC, while preoperative anemia is not a risk factor for PONV after LC.

References
Li N, Dou Y, Liu R, 2025, Comparative Study on the Short-Term Effects and Indicators of Body Stress Response Between Laparoscopic and Small-Incision Cholecystectomy for Gallstones. Henan Journal of Surgery, 31(1): 134–136.
Zhan Z, Bao C, Tang H, et al., 2022, Analysis of 65 Cases of Clinical Experience and Technical Improvements in Stent-Free Laparoscopic Cholecystectomy + Common Bile Duct Incision and Stone Extraction with Primary Suture. Shanxi Medical Journal, 51(15): 1737–1739.
Ni L, Li G, Bao Y, et al., 2026, Relationship Between Serum CCK, D-Lactic Acid, sICAM-1 and Postoperative Gastrointestinal Function Recovery in Elderly Patients Undergoing Laparoscopic Cholecystectomy. Chinese Journal of Gerontology, 46(10): 1745–1748.
Qi X, Hu J, Jia J, 2026, Analysis of Risk Factors for Conversion to Laparotomy in Patients Undergoing Laparoscopic Cholecystectomy. Clinical Research and Practice, 11(14): 77–80.
Ni S, 2026, Analysis of Risk Factors for Conversion to Laparotomy in Laparoscopic Surgery for Calculous Cholecystitis. Zhejiang Journal of Traumatic Surgery, 31(4): 738–741.
Chen L, 2024, The Effect of Electroacupuncture on Postoperative SIRS in Patients Undergoing Laparoscopic Radical Resection of Gastrointestinal Tumors, thesis, Fujian University of Traditional Chinese Medicine.
Liu P, Liu F, Zhao X, et al., 2026, Establishment and Validation of a Nomogram Prediction Model for the Influencing Factors of Surgical Timing Selection and Postoperative Complication Risks in Early Versus Delayed Laparoscopic Surgery for Acute Cholecystitis Patients. Journal of Hepatobiliary Surgery, 34(1): 48–55.
Li C, 2023, Comparison of Surgical Indicators and Postoperative Complications Between Primary Suture and T-Tube Drainage After Laparoscopic Common Bile Duct Incision and Stone Extraction for Common Bile Duct Stones. China Medical Innovation, 20(12): 112–115.
Wang L, Ma L, Wang X, et al., 2026, Report of 1 Case of Deep Cystic Gastritis Diagnosed and Endoscopically Resected by Endoscopic Ultrasonography. Journal of Gastroenterology and Hepatology, 35(4): 519–521.
Li H, Du Y, Lu Z, et al., 2022, The Effect of Different Postoperative Analgesic Methods on Postoperative Nausea and Vomiting in Female Patients Undergoing Laparoscopic Surgery. Inner Mongolia Medical Journal, 54(11): 1299–1304 + 1308.
Sun Y, 2024, The Effect of Remifentanil Target-Controlled Infusion Combined with Ibuprofen Injection on Postoperative Nausea and Vomiting in Female Patients with Motion Sickness Undergoing Gynecological Laparoscopic Surgery, thesis, Jilin University.
Ma J, Wei X, 2021, Research Progress on Opioid Receptor Antagonists in Preventing Postoperative Nausea and Vomiting After General Anesthesia. Clinical Journal of Military Medicine, 49(12): 1406–1408 + 1410.
Share
Back to top
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here
Accept