Objective: To study the effect of minimally invasive spinal trauma surgery on spinal trauma. Methods: After 60 patients with spinal trauma were selected, the patients in observation group was treated by minimally invasive spinal trauma surgery, while the patients in control group was given the routine treatment. Results: After treatment, the observation group improved significantly in operation related indexes, complication rate, pain degree, quality of life, JOA score and 0DI score(P<0.05). Conclusion: Minimally invasive spinal trauma surgery is effective in the treatment of spinal trauma.