Liu Chunying is a famous old Chinese medicine doctor for more than 30 years. He has rich experience in the understanding and treatment of Sjogren's syndrome (SS). Liu Shi systematically discusses the etiology and pathogenesis of SS from the angle of liver depression. In the treatment, it is emphasized that "Muyu Da Zhi" is the first, with the addition and subtraction of the disease, to provide a new idea for the treatment of Sjogren's syndrome from liver depression, and to attach a test case.