Hiccup is a syndrome characterized by continuous sound in the throat, short and frequent sound, and difficult to stop [1]. Although the disease is not life-threatening, it seriously affects the quality of life of patients. Long term intractable hiccup will also have an impact on the psychology of patients and bring great trouble to patients. Hiccup is equivalent to diaphragmatic spasm in western medicine and involves a variety of systemic diseases [2]. At present, the treatment of this disease includes drugs and nerve block, but the curative effect and prognosis are not ideal. Acupuncture and moxibustion, as a green and simple treatment method, has unique curative effect in the treatment of hiccup. Now the test of one case of intractable hiccup caused by ineffective treatment is as follows.