Duodenal fistula refers to the pathological channel formed between the duodenum and the hollow viscera of the human body. If it is connected to a single cavity organ, it is a simple duodenal fistula. If it is connected to ≥ 2 and the hollow viscera are connected, it is a complicated internal duodenal fistula, but simple ones are more common. Once a duodenal fistula develops, it establishes a pathological communication between duodenal contents and related organs, resulting in compromised organ function, infections, malnutrition, bleeding, and other detrimental effects. A patient with choledocholithiasis and choledochoduodenal fistula was treated in our hospital. She underwent laparoscopic left hemihepatectomy + laparoscopic choledochojejunostomy and was discharged 4 days after surgery.