ARTICLE
Volume 10,Issue 7
31 January 2024
Study of Quality Standards of Xiao’er Qingre Enema Preparation in Hospitals
Ruizhong Wang ,
Yurong Zhang ,
Junjun Mao ,
Shaoli Liang ,
Yan Wu ,
Lin Chen
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The First Affiliated Hospital of Xi'an Medical University,
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Department of Pharmacy, The First Affiliated Hospital of Xi’an Medical University, Xi’an 710077, Shaanxi Province, China,
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Department of Pharmacy, The First Affiliated Hospital of Xi’an Medical University, Xi’an 710077, Shaanxi Province, China,
4
Department of Pharmacy, The First Affiliated Hospital of Xi’an Medical University, Xi’an 710077, Shaanxi Province, China,
5
Department of Pharmacy, The First Affiliated Hospital of Xi’an Medical University, Xi’an 710077, Shaanxi Province, China,
6
Department of Pharmacy, The First Affiliated Hospital of Xi’an Medical University, Xi’an 710077, Shaanxi Province, China,
JCNR 2024 , 8(1), 125–132;
https://doi.org/10.26689/jcnr.v8i1.5516
© 2024 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract
Objective: To establish the quality standards for the preparation of Xiao’er Qingre enema in hospitals. Method:Thin-layer chromatography (TLC) was used to identify Radix Isatidis and Glycyrrhizae in the prescription. The content of (R,S)-Goitrin was determined by high-performance liquid chromatography (HPLC). Results: In TLC identification, there was no interference between the negative controls of Radix Isatidis and glycyrrhizae, and the spots were well-separated. The HPLC results of (R,S)-Goitrin showed a good linear relationship between the peak area and concentration within the range of 0.476–95.2 μg·mL-1 (r = 0.9999). Conclusion: The TLC and HPLC methods established in this experiment are simple, reproducible, and specific, making them suitable for the quality control Xiao’er Qingre enema preparation in hospitals.
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