Therapeutic Efficacy of Reduced Glutathione in Emergency Treatment of Organophosphorus Pesticide Poisoning and Its Impact on ALT, AST, CRP, and IL-6 Levels

Yuezhou Wang

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¹ Lianyungang Municipal Oriental Hospital, Lianyungang 222042, Jiangsu Province, China,

JCNR 2024 , 8(11), 185–190; https://doi.org/10.26689/jcnr.v8i11.8987

© 2024 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )

Abstract

Objective: To analyze the efficacy of reduced glutathione (GSH) in the emergency treatment of patients with organophosphorus pesticide poisoning (AOPP). Methods: A total of 100 AOPP patients admitted to the emergency department between January 2022 and January 2024 were selected and randomly divided into two groups. The observation group (n = 50) received GSH combined with conventional treatment, while the reference group (n = 50) received conventional treatment alone. The overall treatment efficacy, serum indicators, and adverse reaction rates were compared. Results: The observation group exhibited a higher overall treatment efficacy compared to the reference group (P < 0.05). Post-treatment, serum indicator levels in the observation group were lower than those in the reference group, and the adverse reaction rate was also lower in the observation group (P < 0.05). Conclusion: GSH can improve the overall treatment efficacy in AOPP patients, protect liver function, reduce inflammatory responses in the body, and minimize post-treatment adverse effects, thus accelerating recovery and demonstrating significant therapeutic advantages.

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