Analysis of the Antidepressant Effects and Mechanisms of Icariin II Based on The GABAergic Nervous System

© 2024 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )

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Abstract

This article summarized the research progress on the antidepressant mechanism of icariin II, mainly elaborating on its mechanism from five aspects: GABAergic nervous system, inflammatory response, oxidative stress, neurotrophic factors, and neurotransmitters in the brain. Its clinical application value was further explored to provide a theoretical basis for the development and utilization of icariin II in treating depression.

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