In this study, we have summarized the coordination of operating room nurses participating in the multidisciplinary team in diagnosing and treating a patient with a large abdominal tumor and multiple pelvic fractures. To perform surgical treatment on patients with various conditions, it is crucial to consider the patients from a holistic perspective. Thus, the existing medical model has shifted from a “disease-centered” approach focusing on single-disciplinary diagnosis and treatment, to a “patient-centered” approach that involves multiple disciplines in diagnosis and therapy. Operating room nurses, as crucial collaborators of surgeons, should make necessary adjustments to enhance their comprehension of patients, improving the overall quality of surgical coordination.