ARTICLE
Volume 10,Issue 7
17 February 2025
Research Progress on Risk Factors for Endometrial Lesions in Asymptomatic Postmenopausal Women with Endometrial Thickening
Yan Song ,
Chengling Zhang ,
Tian Luo ,
Nana Li
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1
Jinan Maternity and Child Health Hospital, Jinan 250000, Shandong Province, China,
2
Department of Gynecology, Jinan Maternity and Child Health Hospital, Jinan 250000, Shandong Province, China,
3
Department of Pathology, Jinan Maternity and Child Health Hospital, Jinan 250000, Shandong Province, China,
4
Department of Women’s Health, Jinan Maternity and Child Health Hospital, Jinan 250000, Shandong Province, China,
JCNR 2025 , 9(1), 94–98;
https://doi.org/10.26689/jcnr.v9i1.9486
© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract
As of 2023, endometrial cancer (EC) ranks second among malignant tumors of the female reproductive system in China, following cervical cancer, posing a significant burden on the country’s healthcare system. Postmenopausal asymptomatic endometrial thickening is primarily benign, often involving endometrial polyps. However, previous clinical studies indicate a relatively high malignancy rate for postmenopausal endometrial polyps, suggesting the necessity for active intervention, particularly in cases with high-risk factors for EC. This article reviews the research progress on risk factors for endometrial lesions in postmenopausal patients with asymptomatic endometrial thickening, aiming to provide insights for clinical diagnosis and treatment.
References
Zheng R, Zhang S, Sun K, et al., 2023, Analysis of the Prevalence of Malignant Tumors in China in 2016. Chinese Journal of Oncology, 45(3): 212–220.
Gu L, Zhang L, Ling Y, 2024, Independent Risk Factors Analysis of Carcinogenesis in Patients with Endometrial Lesions and Correlation Analysis Between Carcinogenesis and Changes in Ultrasonic Parameters. Big Doctor, 9(10): 26–29.
Liu Y, Meng W, He Y, et al., 2023, Correlation Study of Ultrasound, Hysteroscopy, and Histopathological Findings in Asymptomatic Postmenopausal Women with Endometrial Thickening. Journal of Southeast University (Medical Edition), 42(4): 602–606.
Lan S, 2024, The Clinical Value of Hysteroscopy in Asymptomatic Endometrial Thickening After Menopause. Women and Children’s Health Guide, 3(14): 105–108.
Qin Y, Nai M, Wang A, 2024, Effect of LNG-IUS Combined with Goserelin in the Treatment of Asymptomatic Endometrial Thickening After Menopause and its Influence on Sex Hormone-Binding Globulin and Estrogen. Sichuan Journal of Physiological Sciences, 46(9): 1923–1926.
Fu W, Luo Y, Xiong X, 2024, The Application Value of Transvaginal Color Doppler Ultrasound in Patients with Endometrial Lesions. Contemporary Medicine, 30(4): 102–106.
Breijer MC, Peeters JA, Opmeer BC, et al., 2012, Capacity of Endometrial Thickness Measurement to Diagnose Endometrial Carcinoma in Asymptomatic Postmenopausal Women: A Systematic Review and Meta-Analysis. Ultrasound Obstet Gynecol, 40(6): 621–629.
Palermo P, Serva A, Capannolo G, et al., 2021, Asymptomatic Postmenopausal Endometrial Thickening: A Comparison between Transvaginal Ultrasound and Hysteroscopy. The Journal of Minimally Invasive Gynecology, 28(11S): S90–S91.
Liu X, Liu S, Gong F, 2023, Analysis of the Diagnostic and Therapeutic Value of Hysteroscopy in Asymptomatic Endometrial Thickening After Menopause. Chinese Journal of Modern Drug Application, 17(22): 91–94.
Xie J, Wang Z, Shen X, 2023, Pathological Classification and Risk Factor Analysis of Endometrial Thickening in Postmenopausal Women. Hainan Medical Journal, 34(13): 1884–1887.
Wen J, Chen R, Zhao J, et al., 2015, The Application Value of Endometrial Cytology in Postmenopausal Women. Journal of Practical Obstetrics and Gynecology, 31(7): 527–529.
Wu M, 2014, The Application Value of Endometrial Liquid-Based Cytology in the Diagnosis of Endometrial Lesions in Postmenopausal Women. Journal of Clinical Medical Engineering, 21(7): 879–880.
Wang H, Zhao J, Lu C, et al., 2015, Clinicopathological Analysis of Asymptomatic Endometrial Thickening in Obese Postmenopausal Women. Chinese Journal of Modern Medicine, 25(31): 88–91.
Jiang L, Qiao H, Xue L, et al., 2017, Analysis of Potential Malignant Transformation Risk Factors of Asymptomatic Endometrial Polyps in Postmenopausal Women. Chinese Journal of Family Planning, 25(9): 598–600, 604.
Zheng W, 2024, The Effect of Triptorelin Acetate Combined with Sex Hormone Replacement Therapy on the Endometrium of Infertile Patients with PCOS. Medical Innovation of China, 21(16): 124–128.
Wang N, Peng D, Sun X, et al., 2024, Risk Factors and Clinicopathological Features of Endometrial Lesions in Postmenopausal Bleeding. Chinese Journal of Health Care & Nutrition, 42(9): 62–64, 68.
Long A, 2023, Correlation Study Between Endometrial Thickening and Endometrial Lesions in Postmenopausal Women. Practical Gynecologic Endocrinology Electronic Journal, 10(32): 31–33.
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