ARTICLE
Volume 10,Issue 7
31 December 2025
Mediating Effects of Knowledge, Attitudes, and Practice of Rehabilitation on the Relationship between Fatigue and Kinesiophobia in Patients with Coronary Heart Disease
Lele Bi ,
Zhuoting Cheng ,
Li Cheng ,
Taotao Zhang
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1
Hubei University of Medicine, Shiyan 442000, Hubei, China,
JCNR 2025 , 9(12), 56–65;
https://doi.org/10.26689/jcnr.v9i12.12817
© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract
This study aimed to investigate the mediating role of knowledge, attitude, and practice (KAP) in the relationship between fatigue and kinesiophobia in 200 coronary heart disease patients from three Chinese tertiary hospitals. Using validated scales (MFSI-SF, TSK-SV Heart, and the Rehabilitation Exercise Knowledge-Attitude-Practice Scale for Patients ), data analysis via SPSS 25.0 and AMOS 24.0 structural equation modeling identified a significant KAP-mediated pathway (total indirect effect=0.377). KAP of rehabilitation was significantly negatively correlated with fatigue (r=-0.51, p<0.01) and kinesiophobia (r=-0.60, p<0.01), whereas fatigue was significantly positively correlated with kinesiophobia (r=0.678, p<0.01). Results indicate that fatigue amplifies kinesiophobia by compromising KAP of rehabilitation.A significant mediating effect of KAP of rehabilitation on the relationship between fatigue and kinesiophobia was found. Improving patient fatigue and the knowledge, attitudes, and practices of rehabilitation can help reduce kinesiophobia.
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