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Volume 10,Issue 7

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31 December 2025
The Impact of Prophylactic Antibiotic Use in Emergency Treatment of Acute Pancreatitis on the Incidence of Infectious Pancreatic Necrosis
Jianguo Zhou
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1 Department of Emergency, Taizhou People’s Hospital, Taizhou 225300, Jiangsu, China,
JCNR 2025 , 9(12), 329–336; https://doi.org/10.26689/jcnr.v9i12.13482
© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
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Abstract

Objective: To analyze the value of prophylactic antibiotic use in reducing the incidence of pancreatic necrosis in patients with emergency acute pancreatitis (AP). Methods: A total of 70 AP patients who sought medical attention from January 2024 to January 2025 were randomly divided into groups by drawing lots. Group A received prophylactic antibiotic intervention, while Group B received conventional intervention. Results: Group A demonstrated superior outcomes compared to Group B in terms of therapeutic efficacy, duration of symptoms, inflammatory factors, symptom scores, and complication rates, with p < 0.05. Conclusion: Prophylactic antibiotic treatment in emergency AP patients leads to a decrease in inflammatory factor levels, alleviation of symptoms, a reduction in the incidence of infectious pancreatic necrosis, and is safe and effective.

References
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