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Volume 10,Issue 7

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10 March 2025
Exploring the Clinical Value of Combined Detection of Blood Lipids, Blood Glucose, and Liver Function in Non-alcoholic Fatty Liver Disease
Jinyuan Gong
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1 Zhangxizhuang Health Center, Gaoliying Town, Shunyi 101300, Beijing, China,
JCNR 2025 , 9(2), 147–152; https://doi.org/10.26689/jcnr.v9i2.9829
© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
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Abstract

Objective: To study the clinical value of combined detection of blood lipids, blood glucose, and liver function in non-alcoholic fatty liver disease. Methods: 105 patients with non-alcoholic fatty liver disease treated in our hospital from May 2022 to July 2024 were selected as the research subjects. All patients underwent a B-ultrasound examination. According to the severity of the disease, they were divided into group A (mild, n = 35), group B (moderate, n = 44), and group C (severe, n = 26). Another 30 healthy residents who came to the hospital for physical examination during the same period were selected as group D. The differences in blood lipids, blood glucose, and liver function indicators between groups were compared. Results: The triglyceride (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL) levels in groups A, B, and C were higher than those in group D, while the high-density lipoprotein cholesterol (HDL) level was lower (P < 0.05). The fasting plasma glucose (FPG) levels in groups B and C were higher than those in group D (P < 0.05). The TG, LDL, and FPG levels in groups B and C were higher than those in group A (P < 0.05). The TC level in group C was higher than that in group A, while the HDL level was lower (P < 0.05). The TC and FPG levels in group C were higher than those in group B (P < 0.05). The total bilirubin (TBil), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) levels in groups A, B, and C were higher than those in group D (P < 0.05). The TBil and ALT levels in groups B and C were higher than those in group A (P < 0.05). The AST level in group C was higher than that in group A (P < 0.05). The AST and ALT levels in group C were higher than those in group B (P < 0.05). Conclusion: Patients with non-alcoholic fatty liver disease have disordered glucose and lipid metabolism. Blood lipids, blood glucose, and liver function are closely related to the severity of the disease. Strengthening exercise and dietary intervention early on can help control the progression of simple fatty liver disease and reduce the risk of severe liver diseases such as steatohepatitis and cirrhosis.

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