Effects of 0.01% Atropine Eye Drops on Horizontal Meridian Choroidal Thickness Profile in Low to Moderate Myopic Children

² State Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou 310058, Zhejiang, China,

³ Department of Ophthalmology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, Zhejiang, China,

JCNR 2025 , 9(4), 256–264; https://doi.org/10.26689/jcnr.v9i4.10401

© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )

Abstract

Purpose: To examine the changes in choroidal thickness (ChT) after 6-month topical treatment of 0.01% atropine eye drops in myopic children. Methods: A total of 46 low to moderate myopic children aged 8 to 12 years were recruited and received topical 0.01% atropine once a day for 6 months. Spherical equivalent (SE), axial length (AL), and ChT were measured at baseline, 3 months, and 6 months. Results: During the first and second 3-month treatment, there is no significant decrease in progression of SE and AL. Within the range of 3 mm from the temporal side of the fovea to the nasal side, no significant changes in ChT have been observed at any measuring points in low and moderate myopic participants. Changes in ChT were not significantly associated with gender or AL progression. Conclusion: A 6-month topical treatment of 0.01% atropine could not cause significant changes in ChT in myopic children.

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