Objective: To explore the application of “tertiary hospitals-secondary hospitals and nursing care institutions-community-family” four-dimensional linkage care model in peritoneal dialysis patients. Methods: 99 cases of peritoneal dialysis patients were divided into 47 cases in the control group and 52 cases in the intervention group. In the control group, the routine discharge follow-up model was adopted; in the intervention group, the hospital-led medical unit was adopted as the basis of the “tertiary hospitals-secondary hospitals and nursing care institutions-community-family” quadruple linkage care model, and the patients’ systolic blood pressure was compared with those in the control group before and after discharge. The systolic blood pressure, diastolic blood pressure, N-terminal brain natriuretic peptide, and sodium were compared between the two groups. Results: The systolic blood pressure, diastolic blood pressure, N-terminal brain natriuretic peptide, and blood sodium of patients in the intervention group were significantly better than those of the control group (all  P < 0.001). Conclusion: Based on the “tertiary hospital-secondary hospital and nursing home-community-family” quadratic care model, the blood pressure control rate of elderly peritoneal dialysis patients can be increased to meet the standard, reduce the symptoms of the disease, and improve the satisfaction.