Finger reimplantation is a pivotal technique in microsurgery, playing an irreplaceable role in restoring the functional integrity of fingers, maintaining the aesthetic appearance of the hand, ensuring the patient's ability to perform delicate hand operations, and enhancing their social participation and quality of life. This paper reports on the perioperative nursing approach employed in a successful case of replantation involving a single hand with a multi-planar, 20-segment amputation of four fingers. By establishing a specialized nursing team, conducting a comprehensive assessment of the patient's condition, formulating a personalized nursing plan, and implementing precise nursing care, we achieved successful outcomes. After nearly four weeks of meticulous diagnosis, treatment, and nursing, 17 segments of the replanted fingers survived, preserving the functional length of the amputated fingers and maximizing the restoration of hand function. This nursing method provides valuable insights and approaches for effectively managing vascular crises following digital replantation, improving the replantation survival rate, and enhancing patient satisfaction.