Analysis of the Clinical Efficacy of Recombinant Human Interferon α2b Nebulization Inhalation in the Treatment of Hand, Foot, and Mouth Disease in Children

Xia Yang

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¹ Integrated Traditional Chinese and Western Medicine Hospital of Jiuyuan District, Baotou 014060, Inner Mongolia Autonomous Region, China,

JCNR 2025 , 9(9), 88–94; https://doi.org/10.26689/jcnr.v9i9.12278

© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )

Abstract

This clinical study aimed to explore the therapeutic effect of recombinant human interferon α2b nebulization inhalation in the treatment of hand, foot, and mouth disease in children. Sixty-six patients were selected as the research subjects by the random sampling method and divided into a control group and an observation group. The patients in the control group were treated with ribavirin injection and oral lysine-inositol-vitamin B12 solution, while the patients in the observation group received the treatment of the control group combined with recombinant human interferon α2b nebulization inhalation. The clinical effects of the two groups were compared to determine the clinical efficacy of the two treatment plans. The total effective rates of treatment were 78.79% in the control group and 90.91% in the observation group. The research confirmed that the clinical effect of recombinant human interferon α2b nebulization inhalation in the treatment of hand, foot, and mouth disease in children is remarkable. It can significantly improve the symptoms of children with hand, foot, and mouth disease and is suitable for clinical application and promotion.

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