This paper addresses the stringent requirements for sealing technology in high-temperature and high-pressure petrochemical equipment, and introduces the key technologies and performance studies for the domestication of bimetallic self-sealing composite gaskets. The gasket features a composite structure of a double-layer metal framework and flexible graphite, relying on the “pressure self-sealing” mechanism to maintain excellent sealing performance even under high-temperature conditions. The article systematically elaborates on its material process innovations, thermomechanical coupling experiments, and methods for verifying sealing integrity, and establishes a life prediction and engineering risk management system, providing a technical route and theoretical support for the reliable application of high-end sealing components in the petrochemical field in China.