The application of mobile formwork cast-in-situ beam technology is conducive to providing quality assurance for bridge constructions. At the same time, it can improve the overall mechanization level of the construction process and further accelerate the construction progress, so as to shorten the construction period and improve the economic benefits of enterprises. In fact, this construction method has been widely applied. In order to assure a positive outcome from the use of this technology, this paper analyzes the application of mobile formwork cast-in-situ beam technology in bridge construction to provide reference.