Objective: To explore the healing mechanism and effectiveness of immediate implant placement combined with Guided Bone Regeneration (GBR) technique in the oral cavity. Methods: A retrospective analysis was conducted on 93 patients treated at Yongning Dental Clinic (Nanning Xinlantian Medical Investment Co., Ltd.) from September 2021 to September 2024. The patients, aged between 28 and 60, met the criteria for immediate implant placement combined with GBR treatment. The alveolar bone contour plumpness score, osseointegration status, implant stability score, postoperative aesthetic effect, and patient satisfaction score were compared at 1, 3, and 6 months postoperatively. Results: At 1, 3, and 6 months postoperatively, the patients’ alveolar bone contour plumpness was higher than preoperative levels. Postoperatively, osseointegration and implant stability (ISQ value) were improved, and the aesthetic effect was superior to preoperative levels (P < 0.05). The patient satisfaction score was 92.34 ± 3.12, with 94.4% of patients willing to undergo similar treatment again and 97.8% willing to recommend it to others. Conclusion: Immediate implant placement combined with the GBR technique demonstrates significant advantages in promoting postoperative jaw morphology recovery, enhancing osseointegration and implant stability, improving the aesthetic effect of implant restoration, and boosting patient satisfaction. This approach provides a new therapeutic option in the field of oral implantology.