Effect of Laparoscopic Radical Resection and Open Surgery for Liver Cancer and Their Impact on Inflammatory Factor Levels

© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )

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Abstract

Objective: To evaluate the therapeutic effects of laparoscopic radical resection and open surgery for liver cancer. Methods: A total of 80 liver cancer patients admitted to the hospital from January 2023 to January 2025 were selected and equally divided by a random number table. The observation group underwent laparoscopic radical resection, while the reference group underwent open surgery. Perioperative indicators and inflammatory factor levels were compared between the two groups. Results: The observation group exhibited superior perioperative indicators. One day after surgery, the observation group showed excellent inflammatory factor levels, lower fibrosis factor levels, excellent liver function indicators, and a reduced complication rate, with a statistically significant difference between the groups (P < 0.05). Conclusion: Laparoscopic radical resection for liver cancer is minimally invasive, promotes postoperative recovery, reduces postoperative inflammatory responses, inhibits the progression of liver fibrosis, protects liver function, and demonstrates high surgical safety.

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