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Volume 10,Issue 4

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1 April 2026
Research on the Determination of Active Ingredient Content in Compound Preparations by High-Performance Liquid Chromatography
Xintong He
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1 School of Pharmacy, Nanjing University of Chinese Medicine, Taizhou 225300, Jiangsu, China,
PAR 2026 , 10(2), 25–31; https://doi.org/10.26689/par.v10i2.14342
© 2026 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
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Abstract

Compound preparations are characterized by the synergistic enhancement of multiple components, and their quality control directly affects the safety of medication and the stability of therapeutic efficacy. Due to the complex composition of compound preparations and significant differences in the physicochemical properties of various active ingredients, the detection of their content faces technical challenges, such as difficulties in separation and numerous interfering factors. High-performance liquid chromatography (HPLC), with its advantages of high efficiency, high selectivity, and high sensitivity, has become a core method for quality control of compound preparations, providing reliable data support for evaluating the stability and batch consistency of preparations. Currently, there is an increasing variety of traditional Chinese medicine compound preparations. Establishing a specific, stable, and easy-to-operate method for content determination is of great practical significance for improving the quality standards of traditional Chinese medicine and safeguarding the health of the people.

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