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Volume 10,Issue 4

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2 April 2025
Analysis of the Clinical Effect of Pulmicort Respules Inhalation Combined with Cetirizine in the Treatment of Pediatric Asthma and its Influence on Inflammatory Factors in Children
Yong Peng ,  Aimin Li
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1 Jingzhou Hospital Affiliated to Yangtze University, Jingzhou 434020, Hubei, China,
PAR 2025 , 9(2), 71–76; https://doi.org/10.26689/par.v9i2.9963
© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
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Abstract

Objective: To analyze the clinical value of Pulmicort Respules inhalation combined with cetirizine in the treatment of pediatric asthma. Methods: From December 2023 to December 2024, 82 children with asthma admitted to our hospital were randomly divided into a control group and an observation group, with 41 cases in each group. The clinical symptom relief time (shortness of breath, cough, dyspnea, lung wheezing), lung function indicators (FEV1, FVC, FEV1/FVC), inflammatory indicators (TNF-α, IL-6, IL-8), and clinical treatment effects were analyzed in the two groups. Results: The relief time for shortness of breath, cough, dyspnea, and lung wheezing in the observation group was shorter than that in the control group (P < 0.05). After treatment, compared with the control group, the levels of FEV1, FVC, FEV1/FVC, and treatment efficiency in the observation group were higher, while the levels of TNF-α, IL-6, and IL-8 were lower (P < 0.05). Conclusion: The combination of Pulmicort Respules inhalation and cetirizine oral therapy for children with asthma can shorten the improvement time of clinical symptoms, inhibit inflammation, and improve lung function.

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