Growing regulatory demands for industrial safety and environmental protection in the chemical sector necessitate robust operational risk assessment to enhance management efficacy. Here, the HS Chemical Company is evaluated through a multidimensional framework encompassing market dynamics, macroeconomic factors, financial stability, governance, supply chains, and production safety. By integrating the Analytic Hierarchy Process (AHP) with entropy weighting, a hybrid weighting model that mitigates the limitations of singular methods is established. The analysis of this study identifies financial risk (weight: 0.347) and production safety (weight: 0.298) as dominant risk drivers. These quantitative insights offer a basis for resource prioritization and targeted risk mitigation strategies in chemical enterprises.