In recent years, with the advent of the digital era, digital transformation has become a mainstream social trend. As a powerful driving force, digital transformation is profoundly changing the operation mode and management method of enterprise supply chains. Enterprises should seize this opportunity to continuously enhance supply chain resilience. Enhancing enterprise supply chain resilience based on digital transformation can not only improve the supply chain’s resistance and recovery capabilities, but also further enhance its innovation capability. This helps enterprises better respond to various unstable factors and provides protection for promoting the sustainable development of the supply chain. In this regard, this paper first expounds the multi-dimensional value of digital transformation in enhancing enterprise supply chain resilience, and then puts forward effective paths, aiming to provide certain reference for relevant researchers.