This study focuses on the innovative pathways through which the digital economy enables the activation of sleeping resources in the Guangdong-Hong Kong-Macao Greater Bay Area (GBA). It demonstrates the effectiveness of digital technologies in revitalizing idle resources by constructing a “Digital Bay Area” collaborative platform, integrating government and enterprise data resources, and analyzing three typical cases: China Mobile’s “5G + Smart Agriculture” pilot, Dongguan’s “Characteristic Industry IP + Digital Economy” model, and Shenzhen’s cross-border logistics upgrading practice. The research finds that resource activation requires supporting institutional innovations to break regional barriers, which can provide practical references for the optimal allocation of resources in the GBA and facilitate the region’s high-quality development.