In the past 20 years, overseas M&As have gradually become an important investment channel and have an important position in foreign investment. According to the background information of ChemChina’s overseas M&A of Syngenta, the specific circumstances of legal risks, financial risks and cultural risks in the process of ChemChina’s overseas M&A of Syngenta are the starting point for analysis to analyze the reasons for the formation of specific risk factors in this case, summarizing the risk prevention and control measures of Chinese enterprises’ overseas M&A from both macro and micro perspectives.