In recent years, the dairy industry has faced challenges of rising costs and diversified demands, and digital intelligence transformation is the key to supply chain upgrading. Taking M dairy enterprise as an example, this study explores the role of digital transformation and proposes an optimization scheme centered on “bioactivity management.” It focuses on analyzing key technologies such as the Internet of Things (IoT), artificial intelligence (AI), blockchain, and automation: integrating IoT to realize full-chain activity monitoring, applying AI to improve prediction accuracy and flexible production scheduling, using blockchain to build a transparent traceability system, and incorporating bioactivity indicators into the core evaluation system. The research shows that the scheme not only provides a practical guide for M enterprise, but also its strategies have important reference significance for improving the supply chain efficiency of the industry, ensuring quality, and realizing sustainable development.