Effects of Gestational Diabetes Mellitus on Offspring’s Neurobehavioral Development: A Retrospective Cohort Study

¹ School of Public Health, Guilin Medical University, Guilin 541199, Guangxi Zhuang Autonomous Region, China; Weichang Maternal and Child Health Care Hospital, Chengde 068450, Hebei Province, China,

² School of Public Health, Guilin Medical University, Guilin 541199, Guangxi Zhuang Autonomous Region, China,

³ Chengde Maternal and Child Health Care Hospital, Chengde 067000, Hebei Province, China,

⁴ Chengde Maternal and Child Health Care Hospital, Chengde 067000, Hebei Province, China,

⁵ Chengde Maternal and Child Health Care Hospital, Chengde 067000, Hebei Province, China,

⁶ Chengde Maternal and Child Health Care Hospital, Chengde 067000, Hebei Province, China,

⁷ Chengde Maternal and Child Health Care Hospital, Chengde 067000, Hebei Province, China,

AOGR 2024 , 2(1), 13–15; https://doi.org/10.26689/aogr.v2i1.6084

© 2024 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )

Abstract

Objective: To evaluate the association between gestational diabetes mellitus (GDM) and offspring neurobehavioral development. Methods: A total of 280 infants born to mothers with or without GDM were recruited, and their neurobehavioral development was assessed using the Children’s Neuropsychological and Behavioral Scale (CNBS). Results: Infants born to mothers with GDM exhibited significantly lower development quotient (DQ) scores at the 1st, 3rd, 6th, 8th, and 12th months after birth. Conclusion: GDM may adversely affect offspring neurobehavioral development, with this effect persisting despite interventions implemented during pregnancy.

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